Functional Medicine in San Francisco

Most patients who find us have already done the conventional route. The appointments were short, the labs came back "normal," and nobody could explain why they still felt the way they did. That experience is especially common for people with chronic fatigue syndrome (ME/CFS), POTS, hormone imbalance, and PMOS (PCOS) — conditions that are frequently dismissed, misdiagnosed, or undertreated in standard primary care.

A 2019 study published in JAMA Network Open compared over 7,000 patients in functional medicine care against matched patients in conventional primary care. At both six and twelve months, the functional medicine group showed significantly greater improvements in physical and mental health quality of life — the first large-scale clinical evidence that this model of care actually works. At Clarus Health, our functional medicine practice in San Francisco is built around that model: root-cause investigation, physician-level diagnostics, and treatments that go far beyond what a standard panel can offer.

What We Test That Others Don't

Conventional medicine relies on a basic panel. We don't. Every Clarus Health functional medicine relationship begins with diagnostics built around your specific presentation:

• Advanced bloodwork — particle-level lipids (apoB, Lp(a)), inflammatory markers (hs-CRP, homocysteine), insulin resistance, comprehensive thyroid (TSH, Free T3, Free T4, reverse T3, antibodies), iron, ferritin, vitamin D, and micronutrient status.
• POTS and dysautonomia workup — catecholamines (plasma norepinephrine supine and upright), plasma renin activity, aldosterone, complete metabolic panel, CBC, ferritin, and where clinically indicated, autoimmune markers including antinuclear antibodies and ganglionic acetylcholine receptor antibodies. We investigate the autonomic drivers conventional cardiology frequently overlooks.
• Comprehensive hormone testing — estrogen, progesterone, testosterone, DHEA, cortisol, and full thyroid — interpreted in the context of your symptoms and goals. When clinically appropriate, we offer bioidentical hormone replacement therapy (BHRT) integrated directly into your functional medicine care.
• ME/CFS and chronic fatigue workup — mitochondrial function markers, natural killer cell activity where indicated, inflammatory cytokines, HPA axis dysregulation, viral reactivation panels (EBV, HHV-6), and nutritional cofactors. Fatigue that "looks normal" on a basic panel almost never is.
• PMOS (PCOS) evaluation — full androgen panel, LH/FSH ratio, fasting insulin, HOMA-IR, SHBG, and AMH — because PCOS is a metabolic and hormonal condition, and treating it without that data is guesswork.
• Microbiome and GI testing — gut dysfunction drives inflammation, hormone metabolism, immune dysregulation, and fatigue in ways that standard care consistently misses.
• Genomic testing — nutrient metabolism, hormone processing (COMT, MTHFR), and inherited risk, so your protocol is built around your biology.
• Mitochondrial and energy markers — assessed through metabolic, inflammatory, and cellular energy pathways, with IV NAD+, glutathione, alpha-lipoic acid, and targeted micronutrient infusions tailored to your deficiency profile.

What We Treat — Including What You've Been Told Is Untreatable

• Chronic fatigue syndrome (ME/CFS) — we investigate mitochondrial dysfunction, neuroinflammation, HPA axis dysregulation, viral reactivation, and gut-immune crosstalk. For refractory cases, we integrate IV NAD+, glutathione, alpha-lipoic acid, and personalized micronutrient infusions for cellular energy support, Stellate Ganglion Block (SGB) to address autonomic dysregulation, and IV Ketamine for the neurological and pain components that accompany severe ME/CFS. As an anesthesiologist, Dr. Kaveh also performs the Dual Sympathetic Reset (DSR) — a bilateral SGB protocol — for patients whose nervous system dysregulation hasn't responded to standard care.
• POTS (Postural Orthostatic Tachycardia Syndrome) — a comprehensive autonomic workup, volume regulation assessment, and an individualized treatment plan that goes beyond "drink more water and add salt." Stellate Ganglion Block has shown early promise in modulating the sympathetic overdrive that characterizes hyperadrenergic POTS, and the DSR is available for patients whose symptoms remain severe.
• Hormone imbalance, perimenopause, and menopause — estrogen dominance, progesterone deficiency, low testosterone, adrenal dysfunction, and the full spectrum of perimenopausal symptoms. We offer comprehensive BHRT when clinically appropriate.
• PMOS (PCOS — Polycystic Ovary Syndrome) — properly evaluated with full androgen, insulin, and metabolic panels. PCOS is one of the most undertreated conditions in conventional medicine; we don't just put patients on metformin and call it a day.
• Brain fog and cognitive dysfunction — a common feature of ME/CFS, POTS, and hormone imbalance that conventional medicine rarely investigates seriously. We target the metabolic, inflammatory, and hormonal drivers directly, including with IV NAD+, glutathione, and targeted antioxidant infusions based on your lab results.
• Treatment-resistant depression, anxiety, and PTSD — for patients who haven't responded to conventional therapy or medication, we integrate IV Ketamine, Spravato (esketamine), and Stellate Ganglion Block directly into functional medicine care.
• Chronic pain — including fibromyalgia, CRPS, and migraines — conditions that overlap significantly with ME/CFS and POTS. Stellate Ganglion Block and IV Ketamine can offer meaningful relief where standard pain management has failed.
• Cardiovascular and metabolic risk — advanced lipid and inflammatory panels that tell a far more accurate story than a standard cholesterol screen.
• Preventive medicine and early detection — finding the signal before it becomes a diagnosis.

Why Functional Medicine Finds What Conventional Care Misses

• Time — visits long enough to take a real history, review your data, and build a plan. Not a rushed appointment that ends before you've finished explaining your symptoms.
• Diagnostic depth — POTS labs, ME/CFS panels, full hormone and androgen testing, mitochondrial markers, genomics, and microbiome testing — not a basic CBC and a referral.
• Interpretation — your results read against your specific presentation and trajectory, not a population reference range that misses most of what's actually going on.
• Same-day access — direct communication with your physician and a care relationship that deepens as your case evolves.
• Physician-level procedures, in-house — Stellate Ganglion Block and the Dual Sympathetic Reset performed by a Stanford- and Harvard-trained anesthesiologist, alongside IV NAD+, glutathione, alpha-lipoic acid, and personalized micronutrient IVs, IV Ketamine, Spravato, and BHRT — all coordinated by physicians who know your full case.

You deserve a doctor who takes your symptoms seriously.

Begin functional medicine care in San Francisco today.

Whether you're navigating chronic fatigue syndrome (ME/CFS), POTS, hormone imbalance, PMOS (PCOS), or treatment-resistant symptoms that nobody has been able to explain — Clarus Health's functional medicine practice in San Francisco offers a different path. We serve patients across the Bay Area — from Pacific Heights and the Marina to Marin County, the Peninsula, and Silicon Valley — with physician-led root-cause care, advanced diagnostics, and the full clinical toolkit to actually move the needle.