Concierge Primary Care in San Francisco

The average primary care visit in the United States lasts just 18 minutes — not enough time for the questions women across the San Francisco Bay Area are actually asking about hormones, fatigue, brain fog, and longevity. It's why so many women hear "your labs look normal" when they don't feel normal at all.

Clarus Health's San Francisco concierge primary care clinic is built differently. Located in downtown San Francisco and serving women throughout the Bay Area — from Pacific Heights and the Marina to Marin County, the Peninsula, and Silicon Valley — we pair the access of concierge medicine with the deepest diagnostic toolkit in the Bay Area: advanced bloodwork, comprehensive estrogen, progesterone, testosterone, thyroid, and cortisol panels, microbiome and GI testing, urinary diagnostics, and genomic testing — to optimize women's health, hormone balance, and healthspan from the inside out.

What We Test That Others Don't: Advanced Hormones, Microbiome, and Metabolism

Conventional primary care relies on a basic blood panel. We don't. Every Clarus Health primary care relationship begins with diagnostics in high resolution:

• Advanced bloodwork — particle-level lipids (apoB, Lp(a)), inflammatory markers (hs-CRP, homocysteine), insulin resistance, comprehensive thyroid (TSH, Free T3, Free T4, reverse T3, antibodies), iron, ferritin, vitamin D, and micronutrient status.
• Comprehensive hormone testing — estrogen, progesterone (oral and vaginal protocols), testosterone, DHEA, cortisol, and full thyroid — interpreted in the context of your cycle, perimenopause stage, and goals. When indicated, we offer bioidentical hormone replacement therapy (BHRT) and hormone optimization integrated directly into your primary care.
• Microbiome and GI testing — the gut shapes immunity, mood, hormone metabolism (estrogen recycling via the estrobolome), and inflammation — and is the most overlooked system in conventional women's health.
• Urinary diagnostics — bladder health, recurrent UTIs, hormone metabolites, and metabolic byproducts conventional labs miss.
• Genomic testing — nutrient metabolism, hormone processing (COMT, MTHFR), and inherited disease risk, so your protocol is built around your biology, not a population average.
• Mitochondrial and longevity biomarkers — assessed through metabolic, inflammatory, and energy-related markers, with IV NAD+ and targeted nutrition when indicated.

From Hormones to Healthspan — What We Treat

• Hormone optimization and BHRT — perimenopause, menopause, hormone imbalance, low testosterone, estrogen dominance, and progesterone deficiency. Includes oral and vaginal progesterone protocols and full bioidentical hormone replacement therapy when clinically appropriate, including for PMS and PMDD.
• Longevity medicine and healthspan — including evidence-based protocols, metformin for longevity when indicated, biological age testing, and ongoing biomarker optimization.
• Chronic fatigue syndrome (ME/CFS) and unexplained fatigue — we assess mitochondrial, hormonal, neuroinflammatory, and gut-driven causes, and integrate IV NAD+ for chronic fatigue, IV Ketamine, and Stellate Ganglion Block for refractory cases.
• Brain fog and cognitive performance — investigating the metabolic, hormonal, and inflammatory drivers behind it. See our deep dive on how NAD+ therapy can lift brain fog.
• Advanced mental health interventions — for treatment-resistant depression, anxiety, PTSD, and PMDD that haven't responded to conventional therapy or medication. We integrate IV Ketamine, Spravato (esketamine), and Stellate Ganglion Block (SGB) directly into your primary care plan when clinically appropriate.
• Chronic pain — including CRPS, fibromyalgia, and migraines — for the pain conditions conventional medicine struggles to treat. Stellate Ganglion Block and IV Ketamine can offer rapid, lasting relief where opioids and standard regimens have fallen short.
• Cardiovascular and metabolic risk in women — heart disease is the leading cause of death in women, yet women's cardiovascular risk is consistently under-assessed. Advanced lipid and inflammatory panels tell a far more accurate story.
• Bone health and osteoporosis prevention — bone density loss accelerates around perimenopause as estrogen declines. We screen and intervene early.
• Gut, microbiome, and urinary health — recurrent UTIs, bladder concerns, dysbiosis, and digestive function.
• Preventive medicine and early detection — finding the signal before it becomes a diagnosis.

Why Concierge Primary Care Outperforms Conventional Care

• Time — visits long enough to listen, think, and plan, not the 18-minute average.
• Diagnostic depth — advanced lipids, inflammatory markers, full hormone panels, microbiome, urinary diagnostics, and genomics — not a basic CBC and cholesterol screen.
• Interpretation — your data read against your trajectory and goals, not a generic population reference range.
• Same-day access — direct communication with your care team and a relationship that deepens over time.
• Integration — connected to the full Clarus Health toolkit at our San Francisco clinic: BHRT, IV NAD+ and wellness IVs, genomic testing, IV Ketamine, Spravato, and Stellate Ganglion Block — coordinated by physicians who know your case.

You deserve a doctor who knows your whole story.

Begin Concierge Primary Care in San Francisco today.

Whether you're navigating perimenopause, optimizing for the next decade of performance, recovering from chronic fatigue, or simply ready for a primary care relationship that takes your hormones, your bloodwork, and your healthspan seriously — Clarus Health's San Francisco concierge primary care offers a different path forward. We serve women across the San Francisco Bay Area — Pacific Heights, the Marina, SoMa, Marin, the Peninsula, and Silicon Valley — with hormone optimization, BHRT, longevity medicine, IV NAD+, and advanced diagnostics under one San Francisco roof.